SLITRK1 anticorps (PE)

N° du produit ABIN715566

Cet anticorps anti-SLITRK1 est un anticorps Lapin Polyclonal détectant SLITRK1 dans IF (p). Adapté pour Rat, Humain, Souris, Boeuf (Vache), Chien, Porc et Poulet.

Aperçu rapide pour SLITRK1 anticorps (PE) (ABIN715566)

Antigène: SLITRK1 (SLIT and NTRK-Like Family, Member 1 (SLITRK1))

Reactivité: Rat, Humain, Souris, Boeuf (Vache), Chien, Porc, Poulet

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLITRK1 est conjugé à/à la PE

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-SLITRK1 anticorps (PE)

Specificité: Excitation / Emission Wavelengths: 565nm/578nm

Réactivité croisée: Rat (Rattus), Poulet, Chien, Porc, Boeuf (Vache)

Purification: purified by Protein A

Immunogène: KLH conjugated synthetic peptide derived from human Slitrk1

Isotype: IgG

Information d'application

Commentaires:

Excitation / Emission wavelength: 496nm / 578nm

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 µg/µL

Buffer: Aqueous buffered solution containing 100 µg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 4 °C for 12 months

Date de péremption: 12 months

Détails sur SLITRK1

Antigène: SLITRK1 (SLIT and NTRK-Like Family, Member 1 (SLITRK1))

Autre désignation: Slitrk1

Sujet: Slitrk1 is a member of a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the family. For example, Slitrk1 is expressed primarily in mature neurons. Overexpression of Slitrk1 in transfected neuronal cells induced unipolar neurites, while expression of the other Slitrk proteins inhibited neurite outgrowth, suggesting that these proteins are involved in the control of neurite outgrowth. While Slitrk1 variants have been suggested associated with Touretteﾒs Syndrome, it is thought to play only a minor role if at all.

Poids moléculaire: 78-88kDa

ID gène: 114798